Effect of complementary and alternative medicine o… [Ann Oncol. 2012] – PubMed – NCBI


Results from a Korean study comparing users and non-users of complementary and alternative medicine. Not even a placebo effect shows up. Quote:

Compared with nonusers in subgroup analysis, users of alternative medical treatments, prayer, vitamin supplements, mushrooms, or rice and cereal reported clinically significant worse changes in some HRQOL [Health-Related Quality of Life] subscales. Conclusion: While CAM did not provide any definite survival benefit, CAM users reported clinically significant worse HRQOLs.

Effect of complementary and alternative medicine o… [Ann Oncol. 2012] – PubMed – NCBI.


Beware the Nocebo Effect – NYTimes.com

From the placebo to the ‘nocebo’ effect, another example of how our mind can affect our health. Conclusion:

A doctor’s choice of words matters. A team of American anesthesiologists studied women about to give birth who were given an injection of local anesthetic before being administered an epidural. For some women, the injection was prefaced by the statement, “We are going to give you a local anesthetic that will numb the area so that you will be comfortable during the procedure.” For others, the statement was, “You are going to feel a big bee sting; this is the worst part of the procedure.” The perceived pain was significantly greater after the latter statement, which emphasized the downside of the injection.

The nocebo effect presents doctors and nurses with an ethical dilemma: on one hand, they are required to tell patients about the potential complications of a treatment; on the other hand, they want to minimize the likelihood of side effects. But if merely telling patients about side effects increases their likelihood, what is to be done?

Better communication is the answer. When talking with patients, doctors and nurses often say things with unintended negative suggestions, like “it’s just going to bleed a bit” or “you must avoid lifting heavy objects — you don’t want to end up paralyzed.” We recommend more extensive training in communication for doctors and nurses, to help them use the power of their words appropriately. As the great cardiologist Bernard Lown once said, “Words are the most powerful tool a doctor possesses, but words, like a two-edged sword, can maim as well as heal.”

I would likely add that we, as patients, also need to find some techniques to ‘process’ these messages and be more self-aware in our reaction to them.

Beware the Nocebo Effect – NYTimes.com.

Why Placebos Work Wonders – WSJ.com

Fascinating reading on the range of the placebo effect, with the money quote being:

Right now, I think evidence is that placebo changes not the underlying biology of an illness, but the way a person experiences or reacts to an illness.

Attitude would appear to matter!

Why Placebos Work Wonders – WSJ.com.